HCID 12052140, 화합물 → HCID 13883776, 화합물
반응식
[N+:1]([C:4]1[CH:8]=[CH:7][N:6]([CH2:9][CH2:10][CH2:11][CH2:12][C:13]#[N:14])[N:5]=1)([O-])=O>C1COCC1.[Pd]>[NH2:1][C:4]1[CH:8]=[CH:7][N:6]([CH2:9][CH2:10][CH2:11][CH2:12][C:13]#[N:14])[N:5]=1참가 물질
4
실험 절차
To a solution of 5-(3-nitropyrazol-1-yl)valeronitrile (9.16 g.) in dry THF (200 ml.) was added 5% w/w palladium on carbon (1.8 g.). The mixture was stirred at 20° under an atmosphere of hydrogen. 3.2 Liters of hydrogen were absorbed over 4 hours. The catalyst was filtered off and the filtrate was evaporated in vacuo to give 5-(3-aminopyrazol-1-yl)valeronitrile as an oil.
후처리
- custom3.2 Liters of hydrogen were absorbed over 4 hours
- filtrationThe catalyst was filtered off
- customthe filtrate was evaporated in vacuo
출처 및 근거
- ORD 기록
- ord-e1445fdfb2d24f5ab79428792784cf8f
- 출처 데이터셋
- uspto-grants-1989_01
- 특허 번호
- US04795755
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