Isoquinoline-5-sulfonyl chloride hydrochloride → HCID 21278320, 화합물

HRID 2291948

반응식

HRID 2291948 반응식
Cl.[CH:2]1[C:11]2[CH:10]=[CH:9][CH:8]=[C:7]([S:12](Cl)(=[O:14])=[O:13])[C:6]=2[CH:5]=[CH:4][N:3]=1.[OH:16][CH:17]1[CH2:21][CH:20]([CH3:22])[NH:19][CH2:18]1>>[CH:2]1[C:11]2[CH:10]=[CH:9][CH:8]=[C:7]([S:12]([N:19]3[CH:20]([CH3:22])[CH2:21][CH:17]([OH:16])[CH2:18]3)(=[O:14])=[O:13])[C:6]=2[CH:5]=[CH:4][N:3]=1

참가 물질

3

반응물 2

HCID 13116932Isoquinoline-5-sulfonyl chloride hydrochlorideHCID 219737795-Methylpyrrolidin-3-ol

생성물 1

HCID 21278320HCID 21278320, 화합물

실험 절차

In substantially the same manner as in Example 11, 2.64 g of 5-isoquinolinesulfonyl chloride hydrochloride was reacted with 2.0 g of 3-hydroxy-5-methylpyrrolidine to obtain 1-(5-isoquinolinesulfonyl)-3-hydroxy-5-methylpyrrolidine.

출처 및 근거

ORD 기록
ord-03e8df5658404f978996ea1be23a6610
출처 데이터셋
uspto-grants-1989_01
특허 번호
US04798897

연결된 노트

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