Benzene → 2-(2',3'-Difluorophenyl)-5-n-heptyl-1,3-dioxane

HRID 2292434노트

반응식

HRID 2292434 반응식
[CH2:1]([CH:8]([CH2:11][OH:12])[CH2:9][OH:10])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7].[F:13][C:14]1[C:21]([F:22])=[CH:20][CH:19]=[CH:18][C:15]=1[CH:16]=O.C1(C)C=CC(S(O)(=O)=O)=CC=1.C1C=CC=CC=1>C1(C)C=CC=CC=1>[F:13][C:14]1[C:21]([F:22])=[CH:20][CH:19]=[CH:18][C:15]=1[CH:16]1[O:10][CH2:9][CH:8]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7])[CH2:11][O:12]1

참가 물질

6

반응물 4

HCID 241BenzeneHCID 6101p-Toluenesulfonic acidHCID 1376642,3-DifluorobenzaldehydeHCID 2255562-Heptylpropane-1,3-diol

생성물 1

HCID 214779562-(2',3'-Difluorophenyl)-5-n-heptyl-1,3-dioxane

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

Quantities: compound from Example 8 (27 g, 0.155 mol), 2,3-difluorobenzaldehyde (21.5 g, 0.15 mol) and 4-toluenesulphonic acid (100 mg). The experimental procedure was as described in Example 11 except using dry benzene instead of dry toluene.

출처 및 근거

ORD 기록
ord-b99c5f95dc184a2fb258b66852360779
출처 데이터셋
uspto-grants-1997_11
특허 번호
US05683623

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