Phenethylamine → 1-cyclopropyl-1,2,3,4-tetrahydroisoquinoline

HRID 2293131노트

반응식

[CH2:1]([NH2:9])[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[CH:10]1([C:13](Cl)=O)[CH2:12][CH2:11]1>>[CH:10]1([CH:13]2[C:8]3[C:3](=[CH:4][CH:5]=[CH:6][CH:7]=3)[CH2:2][CH2:1][NH:9]2)[CH2:12][CH2:11]1

참가 물질

반응물 2

HCID 1001Phenethylamine

HCID 77637Cyclopropanecarbonyl chloride

생성물 1

HCID 115573681-cyclopropyl-1,2,3,4-tetrahydroisoquinoline

실험 절차

In accordance with the same procedures as in Preparation 1-1, except that 12.5 ml of phenethylamine (0.1M) and 10 ml of cyclopropane carbonylchloride(0.11M) were used as starting materials, 2.5 g of the title compound was prepared.

후처리

customIn accordance with the same procedures as in Preparation 1-1

출처 및 근거

ORD 기록: ord-49ff28f061c146c3a2fe6ff3b49b80de
출처 데이터셋: uspto-grants-1997_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05686458

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