참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Nitric Acid | HCID 944 | — |
| 반응물 | 2-Methoxy-4-methylbenzoic acid | HCID 597164 | — |
| 용매 | Sulfuric Acid | HCID 1118 | — |
| 생성물 | 2-Methoxy-4-methyl-5-nitrobenzoic acid | HCID 21477051 | — |
반응 단계
A 2.00 g portion of 2-methoxy-4-methylbenzoic acid was dissolved in 10 ml of sulfuric acid. With stirring at 0° C., 0.88 ml of concentrated nitric acid was added thereto dropwise. After 4 hours of stirring at room temperature, and ice water was added. The thus formed crystals were collected by filtration, dried under a reduced pressure and then purified by column chromatography (chloroform:methanol=30:1) to give 1.32 g of 2-methoxy-4-methyl-5-nitrobenzoic acid as yellow crystals.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05686482 |
|---|
| 출처 데이터셋 | uspto-grants-1997_11 |
|---|
| ORD ID | ord-87f4a387079241a9818c7c708286625e |
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| 출처 메모 | uspto-grants-1997_11 |
|---|
