3-Chloro-4-methoxybenzene-1-sulfonyl chloride → 5-[(3-Chloro-4-methoxyphenyl)sulfonyl]-4-ethyl-7-(trifluoromethyl)-4,5-dihydropyrrolo[1,2-a]quinoxaline

HRID 229382노트

반응식

HRID 229382 반응식
[CH2:1]([CH:3]1[NH:12][C:11]2[C:6](=[CH:7][CH:8]=[C:9]([C:13]([F:16])([F:15])[F:14])[CH:10]=2)[N:5]2[CH:17]=[CH:18][CH:19]=[C:4]12)[CH3:2].[CH3:20][O:21][C:22]1[CH:27]=[CH:26][C:25]([S:28](Cl)(=[O:30])=[O:29])=[CH:24][C:23]=1[Cl:32]>>[Cl:32][C:23]1[CH:24]=[C:25]([S:28]([N:12]2[C:11]3[C:6](=[CH:7][CH:8]=[C:9]([C:13]([F:16])([F:15])[F:14])[CH:10]=3)[N:5]3[CH:17]=[CH:18][CH:19]=[C:4]3[CH:3]2[CH2:1][CH3:2])(=[O:30])=[O:29])[CH:26]=[CH:27][C:22]=1[O:21][CH3:20]

참가 물질

3

반응물 2

HCID 167674273-Chloro-4-methoxybenzene-1-sulfonyl chlorideHCID 690604574-Ethyl-7-trifluoromethyl-4,5-dihydropyrrolo[1,2-a]quinoxaline

생성물 1

HCID 690717205-[(3-Chloro-4-methoxyphenyl)sulfonyl]-4-ethyl-7-(trifluoromethyl)-4,5-dihydropyrrolo[1,2-a]quinoxaline

실험 절차

The title compound was prepared from the product of Example 55, step 1 and 4-methoxy-3-chloro benzenesulfonyl chloride according to the procedure of Example 4 to yield light brown crystals, mp 126-129° C.

후처리

  1. customto yield light brown crystals, mp 126-129° C.

출처 및 근거

ORD 기록
ord-de1138f5ff0f4cd69d339716b2933e57
출처 데이터셋
uspto-grants-2009_07
특허 번호
US07563793B2

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