HCID 21473739, 화합물 → HCID 10107954, 화합물
반응식
[CH2:1]([O:3][C:4](/[CH:6]=[CH:7]/[C:8]1[S:12][C:11]([C:13]([O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:14])=[CH:10][CH:9]=1)=[O:5])[CH3:2]>C(O)C.[C].[Pd]>[CH2:1]([O:3][C:4]([CH2:6][CH2:7][C:8]1[S:12][C:11]([C:13]([O:15][C:16]([CH3:17])([CH3:19])[CH3:18])=[O:14])=[CH:10][CH:9]=1)=[O:5])[CH3:2]참가 물질
4
실험 절차
The t-butyl 5-(2-ethoxycarbonyl-E-ethenyl)-2-thiophenecarboxylate (7.58 g, 26.8 mmol) prepared in the Preparative Example 14 was catalytically reduced with 10% palladium-carbon (1.05 g) in ethanol at room temperature. After the completion of the reaction, the catalyst was filtered out and the filtrate was concentrated and evaporated to dryness in a vacuum. 7.6 g of the title compound was obtained.
후처리
- customAfter the completion of the reaction
- filtrationthe catalyst was filtered out
- concentrationthe filtrate was concentrated
- customevaporated to dryness in a vacuum
출처 및 근거
- ORD 기록
- ord-49565914b6584174a4112704c048d702
- 출처 데이터셋
- uspto-grants-1997_11
- 특허 번호
- US05688800
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