Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(Bis(4-fluorophenyl)methylene)piperidine → 6-Acetyl-3-(2-(4-(bis(4-fluorophenyl)methylene)piperidin-1-yl)ethyl)-4,5,6,7-tetrahydro-2-methylthieno[2,3-c]pyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(Bis(4-fluorophenyl)methylene)piperidine | HCID 2724436 | — |
| 반응물 | 6-Acetyl-3-(2-chloroethyl)-4,5,6,7-tetrahydro-2-methylthieno[2,3-c]pyridine | HCID 21471856 | — |
| 생성물 | 6-Acetyl-3-(2-(4-(bis(4-fluorophenyl)methylene)piperidin-1-yl)ethyl)-4,5,6,7-tetrahydro-2-methylthieno[2,3-c]pyridine | HCID 21471767 | 46.9% |
반응 단계
The reaction and procedure were conducted in a similar manner as in Example 24 using 0.7 g of 6-acetyl-3-(2-chloroethyl)-4,5,6,7-tetrahydro-2-methylthieno[2,3-c]pyridine and 0.6 g of 4-(bis(4-fluorophenyl)-methylene)piperidine to give 0.5 g of 6-acetyl-3-(2-(4-(bis(4-fluorophenyl)methylene)piperidin-1-yl)ethyl)-4,5,6,7-tetrahydro-2-methylthieno[2,3-c]pyridine as an oil, m.p. 209°-211° C. as axalate thereof.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05691330 |
| 출처 데이터셋 | uspto-grants-1997_11 |
| ORD ID | ord-c7deac45abb14f8f906f9f894f3a3fa3 |
| 출처 메모 | uspto-grants-1997_11 |