Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Benzylpiperazine → 1-(2-Phenoxy-2-methylpropionyl)-4-benzylpiperazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Benzylpiperazine | HCID 75994 | — |
| 반응물 | 2-Methyl-2-phenoxypropanoyl chloride | HCID 13111191 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 1-(2-Phenoxy-2-methylpropionyl)-4-benzylpiperazine | HCID 10616992 | — |
반응 단계
A solution of 0.01 mol of 2-phenoxyisobutyric acid chloride (obtained by reaction of thionyl chloride with 2-phenoxyisobutyric acid) in 100 ml of methylene chloride is introduced into an Erlenmeyer flask containing a solution of 0.01 mol of 1-benzylpiperazine in 100 ml of methylene chloride. The mixture is stirred for 5 hours at room temperature, filtered and evaporated to dryness. The residue is taken up in water, basified and extracted with chloroform. The organic phases are combined, dried and evaporated.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05691340 |
| 출처 데이터셋 | uspto-grants-1997_11 |
| ORD ID | ord-8c2a58b838194708a696d0cbb1851650 |
| 출처 메모 | uspto-grants-1997_11 |