Phosgene → 2-Chloro-3-pyridinesulfonylisocyanate

HRID 2295249노트

반응식

HRID 2295249 반응식
[Cl:1][C:2]1[C:7]([S:8]([NH:11][C:12](=[O:18])NCCCC)(=[O:10])=[O:9])=[CH:6][CH:5]=[CH:4][N:3]=1.C(Cl)(Cl)=O>C1(C)C(C)=CC=CC=1>[Cl:1][C:2]1[C:7]([S:8]([N:11]=[C:12]=[O:18])(=[O:9])=[O:10])=[CH:6][CH:5]=[CH:4][N:3]=1

참가 물질

4

반응물 2

HCID 6371PhosgeneHCID 12383441HCID 12383441, 화합물

생성물 1

HCID 130384352-Chloro-3-pyridinesulfonylisocyanate

시약·촉매·용매 1

HCID 7237O-Xylene용매

실험 절차

To 125 ml of dry xylene was added with stirring 20.7 g of 2-chloro-N-(butylcarbamoyl)-3-pyridinesulfonamide. This solution was heated to reflux, and phosgene added until no further uptake of this gas was observed. It was then cooled, filtered and the solvent removed in vacuo to yield 2-chloro-3-pyridinesulfonylisocyanate as an oil Bp 108°-110° (0.7 mm Hg) and showing a sharp absorption peak in the infrared region at 2220 cm-1.

후처리

  1. temperatureThis solution was heated
  2. temperatureto reflux
  3. temperatureIt was then cooled
  4. filtrationfiltered
  5. customthe solvent removed in vacuo

출처 및 근거

ORD 기록
ord-2e145d4127e149cc899d0287e6686521
출처 데이터셋
uspto-grants-1984_01
특허 번호
US04424073

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