Tert-Butylhydroquinone → HCID 54443355, 화합물

HRID 2295331노트

반응식

HRID 2295331 반응식
[CH3:1][N:2]([CH3:6])[CH2:3][CH2:4][NH2:5].[CH:7]([C:9]1[O:10][C:11](=[O:16])[C:12]([CH3:15])([CH3:14])[N:13]=1)=[CH2:8].O1C=CNC1=O.C(C1C=C(O)C=CC=1O)(C)(C)C>C1C=CC=CC=1>[CH3:1][N:2]([CH3:6])[CH2:3][CH2:4][NH:5][C:11](=[O:16])[C:12]([CH3:15])([NH:13][C:9](=[O:10])[CH:7]=[CH2:8])[CH3:14]

참가 물질

6

반응물 4

HCID 16043Tert-ButylhydroquinoneHCID 66053N,N-DimethylethylenediamineHCID 1861144-Oxazolin-2-oneHCID 98127942-Ethenyl-4,4-dimethyl-1,3-oxazol-5(4H)-one

생성물 1

HCID 54443355HCID 54443355, 화합물

시약·촉매·용매 1

HCID 241Benzene용매2회

실험 절차

A solution of 100 g. of N,N-dimethylethylenediamine in 40 cc. of benzene was added dropwise to a stirring solution of 16.4 g. of 2-vinyl-4,4-dimethyl-5-oxazolone in 50 cc. of benzene. The oxazolone solution contained a few milligrams of t-butylhydroquinone as a polymerization inhibitor. An external water bath was used to maintain the resultant solution at about 25° C. The solution was stirred about 2 hours, filtered through Celite, and evaporated. The residue after evaporation was triturated with hexane and the mixture filtered to provide N-(N',N'-dimethyl-β-aminoethyl)-2-methyl-2-acrylamidopropanoic acid amide as a white solid.

후처리

  1. customAn external water bath was used
  2. filtrationfiltered through Celite
  3. customevaporated
  4. customThe residue after evaporation
  5. customwas triturated with hexane
  6. filtrationthe mixture filtered

출처 및 근거

ORD 기록
ord-f684a47319c144afa7e7365e4b62a48c
출처 데이터셋
uspto-grants-1984_01
특허 번호
US04424272

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