Water → HCID 20472952, 화합물

HRID 2295956노트

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HRID 2295956 반응식
[C:1]1(=[O:11])[NH:5][C:4](=[O:6])[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12.[C:12]([C:14]1[CH:22]=[CH:21][C:20]([O:23][C:24]2[CH:29]=[CH:28][C:27]([Cl:30])=[CH:26][C:25]=2[Cl:31])=[CH:19][C:15]=1[C:16](Cl)=[O:17])#[N:13].O>CN(C)C=O>[C:12]([C:14]1[CH:22]=[CH:21][C:20]([O:23][C:24]2[CH:29]=[CH:28][C:27]([Cl:30])=[CH:26][C:25]=2[Cl:31])=[CH:19][C:15]=1[C:16]([N:5]1[C:1](=[O:11])[C:2]2=[CH:10][CH:9]=[CH:8][CH:7]=[C:3]2[C:4]1=[O:6])=[O:17])#[N:13]

참가 물질

5

반응물 3

HCID 962WaterHCID 6809PhthalimideHCID 202299172-Cyano-5-(2,4-dichlorophenoxy)benzoyl chloride

생성물 1

HCID 20472952HCID 20472952, 화합물

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

The N-potassium salt of phthalimide (0.025 mole) dissolved in dimethylformamide (50 ml) and 2-cyano-5-(2,4-dichlorophenoxy)benzoyl chloride (0.025 mole) are charged into a glass reaction vessel equipped with a mechanical stirrer and thermometer. The reaction mixture is stirred at room temperature for a period of about 8 hours. After this time the mixture is poured into water (150 ml) and is extracted twice with toluene. The toluene extracts are combined and stripped of solvent leaving a solid residue. This residue is recrystallized to yield the desired product N-[2-cyano-5-(2,4-dichlorophenoxy)benzoyl]phthalimide.

후처리

  1. customequipped with a mechanical stirrer
  2. extractionis extracted twice with toluene
  3. customleaving a solid residue
  4. customThis residue is recrystallized

출처 및 근거

ORD 기록
ord-f4a91bd0bb634622ad18538ea70c8ffa
출처 데이터셋
uspto-grants-1984_01
특허 번호
US04427441

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