p-Toluenesulfonic acid → 3,3',6,6'-Tetramethyl-2,2'-biphenol

HRID 2297083노트

반응식

HRID 2297083 반응식
C([C:5]1[C:10]([CH3:11])=[C:9]([OH:12])[C:8]([C:13]2[C:14]([OH:25])=[C:15]([CH3:24])[C:16](C(C)(C)C)=[CH:17][C:18]=2[CH3:19])=[C:7]([CH3:26])[CH:6]=1)(C)(C)C.C1(C)C=CC(S(O)(=O)=O)=CC=1>O>[CH3:19][C:18]1[CH:17]=[CH:16][C:15]([CH3:24])=[C:14]([OH:25])[C:13]=1[C:8]1[C:9]([OH:12])=[C:10]([CH3:11])[CH:5]=[CH:6][C:7]=1[CH3:26]

참가 물질

4

반응물 2

HCID 6101p-Toluenesulfonic acidHCID 185446495,5'-Bis(t-butyl)-3,3',6,6'-tetramethyl-2,2'-biphenol

생성물 1

HCID 113569233,3',6,6'-Tetramethyl-2,2'-biphenol

시약·촉매·용매 1

HCID 962Water용매

실험 절차

To a 50 mL flask were added 0.5 g of 5,5′-Bis(t-butyl)-3,3′,6,6′-tetramethyl-2,2′-biphenol, 5 mL of xylenes and 0.05 g of p-toluenesulfonic acid. The mixture was refluxed for about 2 hours. The mixture was cooled and water added. The mixture was extracted with hexanes; the organic layer was washed with water and dried over MgSO4. After removing the solvent, the residue was recrystallized from petroleum ether.

후처리

  1. temperatureThe mixture was refluxed for about 2 hours
  2. temperatureThe mixture was cooled
  3. extractionThe mixture was extracted with hexanes
  4. washthe organic layer was washed with water
  5. dry with materialdried over MgSO4
  6. customAfter removing the solvent
  7. customthe residue was recrystallized from petroleum ether

출처 및 근거

ORD 기록
ord-35a99cd3e2f24e8699bdfde0ecadada8
출처 데이터셋
uspto-grants-2002_12
특허 번호
US06489517B1

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