p-Toluenesulfonic acid → Allyl-(1-methyl-pent-4-enylidene)-amine Allyl-(1-methyl-pent-4-enyl)-amine

HRID 229790노트

반응식

HRID 229790 반응식
[CH3:1][C:2](=O)[CH2:3][CH2:4][CH:5]=[CH2:6].[CH2:8]([NH2:11])[CH:9]=[CH2:10].[C:12]1(C)[CH:17]=[CH:16][C:15](S(O)(=O)=O)=[CH:14][CH:13]=1>C(Cl)Cl>[CH2:8]([NH:11][CH:2]([CH3:1])[CH2:3][CH2:4][CH:5]=[CH2:6])[CH:9]=[CH2:10].[CH2:8]([N:11]=[C:16]([CH3:15])[CH2:17][CH2:12][CH:13]=[CH2:14])[CH:9]=[CH2:10]

참가 물질

5

반응물 3

HCID 6101p-Toluenesulfonic acidHCID 7853AllylamineHCID 79895-Hexene-2-one

생성물 1

HCID 22036684Allyl-(1-methyl-pent-4-enylidene)-amine Allyl-(1-methyl-pent-4-enyl)-amine

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

Hex-5-en-2-one (9.8 g, 11.6 ml, 100 mmol) was added to a stirred solution of allylamine (8.55 mmol, 11.25 ml, 150 mmol), 4 Angstrom molecular sieves (52 g), and p-toluene sulfonic acid (10 mg) in CH2Cl2 (200 ml) and was stirred overnight. The reaction mixture was concentrated in vacuo by rotary evaporation and was used in the next reaction without further purification (13 g, 95%). Electrospray mass spec: M+H+=137.9

후처리

  1. concentrationThe reaction mixture was concentrated in vacuo by rotary evaporation
  2. customwas used in the next reaction without further purification (13 g, 95%)

출처 및 근거

ORD 기록
ord-0849a3b1ed544e909d3f11f35a3bce59
출처 데이터셋
uspto-grants-2009_07
특허 번호
US07563784B2

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