p-Toluenesulfonic acid → N-[1-(1H-1,2,3-benzotriazol-1-yl)-2,2-dichloropropyl]4-chlorobenzamide

반응식

[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([NH2:8])=[O:7])=[CH:4][CH:3]=1.[Cl:11][C:12]([Cl:16])([CH3:15])[CH:13]=O.[NH:17]1[C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=2[N:19]=[N:18]1.C1(C)C=CC(S(O)(=O)=O)=CC=1>>[N:17]1([CH:13]([NH:8][C:6](=[O:7])[C:5]2[CH:9]=[CH:10][C:2]([Cl:1])=[CH:3][CH:4]=2)[C:12]([Cl:16])([Cl:11])[CH3:15])[C:21]2[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=2[N:19]=[N:18]1

참가 물질

반응물 4

HCID 6101p-Toluenesulfonic acid

HCID 120844-Chlorobenzamide

HCID 109754962,2-Dichloropropanal

HCID 178418385HCID 178418385, 화합물

생성물 1

HCID 18770573N-[1-(1H-1,2,3-benzotriazol-1-yl)-2,2-dichloropropyl]4-chlorobenzamide

실험 절차

4-Chlorobenzamide, the product from Example 24A, benzotriazole, and p-toluenesulfonic acid were processed as described in Example 1C to provide the title compound.

출처 및 근거

ORD 기록: ord-52beb038eed142ab944c9d601a0752e1
출처 데이터셋: uspto-grants-2002_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06495576B2

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