Dimethylformamide → 2-Bromo-1-(3-methylbut-2-enylthio)benzene
반응식
[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[SH:8].CN(C=O)C.C(=O)([O-])[O-].[K+].[K+].Br[CH2:21][CH:22]=[C:23]([CH3:25])[CH3:24]>O>[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8][CH2:21][CH:22]=[C:23]([CH3:25])[CH3:24]참가 물질
6
실험 절차
19.30 g (102.0 mmol) of 2-bromothiophenol, 160 ml of DMF and 15.50 g (112.0 mmol) of potassium carbonate are introduced into a three-necked flask. 13 ml (112.0 mmol) of 1-bromo-3-methyl-2-butene are added dropwise and the reaction mixture is stirred at room temperature for two hours. It is poured into water and extracted with ethyl acetate and the organic phase is separated by settling, washed with water, dried over magnesium sulphate and evaporated. 26.00 g (99%) of the expected compound are collected in the form of an orangey oil.
후처리
- extractionextracted with ethyl acetate
- customthe organic phase is separated
- washwashed with water
- dry with materialdried over magnesium sulphate
- customevaporated
- custom26.00 g (99%) of the expected compound are collected in the form of an orangey oil
출처 및 근거
- ORD 기록
- ord-cc4dd4a925134e97806965f18a207e98
- 출처 데이터셋
- uspto-grants-2005_02
- 특허 번호
- US06849658B2
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