1,4-Dioxa-8-azaspiro(4.5)decane → HCID 18342989, 화합물

반응식

[CH2:1]1[O:10][C:4]2([CH2:9][CH2:8][NH:7][CH2:6][CH2:5]2)[O:3][CH2:2]1.[Cl:11][C:12]1[C:17]([O:18][CH3:19])=[CH:16][C:15]([C:20]2[CH:25]=[C:24]([CH2:26]Cl)[CH:23]=[CH:22][N:21]=2)=[CH:14][C:13]=1[O:28][CH3:29]>>[CH2:1]1[O:10][C:4]2([CH2:9][CH2:8][N:7]([CH2:26][C:24]3[CH:23]=[CH:22][N:21]=[C:20]([C:15]4[CH:16]=[C:17]([O:18][CH3:19])[C:12]([Cl:11])=[C:13]([O:28][CH3:29])[CH:14]=4)[CH:25]=3)[CH2:6][CH2:5]2)[O:3][CH2:2]1

참가 물질

반응물 2

HCID 674351,4-Dioxa-8-azaspiro(4.5)decane

HCID 22557787HCID 22557787, 화합물

생성물 1

HCID 18342989HCID 18342989, 화합물

실험 절차

4-Piperidone ethylene ketal (573 mg) and 2-(4-chloro-3,5-dimetoxyphenyl)-4-chloromethylpyridine (1.19 g) were condensed in the same manner as described in Example 2 to give the title compound.

후처리

customcondensed in the same manner

출처 및 근거

ORD 기록: ord-e82f7613edf7495a91909424124b4bb2
출처 데이터셋: uspto-grants-2002_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06498169B1

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