N-[3-(3-butyl-7-dimethylamino-3-ethyl-4-hydroxy-1,1-dioxo-2,3,4,5-tetrahydro-1H-benzo[b]thiepin-5-yl)phenyl]-5-bromopentanamide → N-[3-(3-Butyl-7-dimethylamino-3-ethyl-4-hydroxy-1,1-dioxo-2,3,4,5-tetrahydro-1H-benzo[b]thiepin-5-yl)-phenyl]-5-{4-[3-(3-hydroxy-3-phenylpropyl)-2-(4-methoxyphenyl)-4-oxoazetidin-1-yl]benzylamino}pentanamide

반응식

[CH2:1]([C:5]1([CH2:36][CH3:37])[CH2:11][S:10](=[O:13])(=[O:12])[C:9]2[CH:14]=[CH:15][C:16]([N:18]([CH3:20])[CH3:19])=[CH:17][C:8]=2[CH:7]([C:21]2[CH:22]=[C:23]([NH:27][C:28](=[O:34])[CH2:29][CH2:30][CH2:31][CH2:32]Br)[CH:24]=[CH:25][CH:26]=2)[CH:6]1[OH:35])[CH2:2][CH2:3][CH3:4].[NH2:38][CH2:39][C:40]1[CH:45]=[CH:44][C:43]([N:46]2[CH:49]([C:50]3[CH:55]=[CH:54][C:53]([O:56][CH3:57])=[CH:52][CH:51]=3)[CH:48]([CH2:58][CH2:59][CH:60]([OH:67])[C:61]3[CH:66]=[CH:65][CH:64]=[CH:63][CH:62]=3)[C:47]2=[O:68])=[CH:42][CH:41]=1>CN(C)C=O>[CH2:1]([C:5]1([CH2:36][CH3:37])[CH2:11][S:10](=[O:13])(=[O:12])[C:9]2[CH:14]=[CH:15][C:16]([N:18]([CH3:20])[CH3:19])=[CH:17][C:8]=2[CH:7]([C:21]2[CH:22]=[C:23]([NH:27][C:28](=[O:34])[CH2:29][CH2:30][CH2:31][CH2:32][NH:38][CH2:39][C:40]3[CH:45]=[CH:44][C:43]([N:46]4[C:47](=[O:68])[CH:48]([CH2:58][CH2:59][CH:60]([OH:67])[C:61]5[CH:66]=[CH:65][CH:64]=[CH:63][CH:62]=5)[CH:49]4[C:50]4[CH:51]=[CH:52][C:53]([O:56][CH3:57])=[CH:54][CH:55]=4)=[CH:42][CH:41]=3)[CH:24]=[CH:25][CH:26]=2)[CH:6]1[OH:35])[CH2:2][CH2:3][CH3:4]