참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Diethylamine | HCID 8021 | — |
| 반응물 | Benzoic acid, 3-(chlorosulfonyl)- | HCID 77641 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 3-(Diethylsulfamoyl)benzoic acid | HCID 794595 | — |
반응 단계
To a solution of 3-(chlorosulfonyl)benzoic acid (1.02 g, 4.62 mmol) in CH2Cl2 (100 mL) at 0° C. was added diethylamine (2.4 mL, 23 mmol). The resulting mixture was stirred at 0° C. for 3 h then worked up by adding 2N aqueous HCl and extracting 3× with EtOAc. The combined organic was washed with brine then dried over MgSO4 and concentrated under reduced pressure. The residue was used without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06498165B1 |
|---|
| 출처 데이터셋 | uspto-grants-2002_12 |
|---|
| ORD ID | ord-90ed747076b34b5eba680df517cd9781 |
|---|
| 출처 메모 | uspto-grants-2002_12 |
|---|
