Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pyridine → Isobutyl 2-bromopropionate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pyridine | HCID 1049 | — |
| 반응물 | Isobutanol | HCID 6560 | — |
| 반응물 | Propanoyl bromide, 2-bromo- | HCID 79047 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | Isobutyl 2-bromopropionate | HCID 522337 | — |
반응 단계
To a mixture of iso-butanol and 1.0 equivalent of pyridine in dry diethyl ether was added dropwise 1.3 equivalents of 2-bromopropionyl bromide at 0° C. After stirring at room temperature for 16 hours, the reaction was diluted with diethyl ether, washed with 1N HCl, water, aqueous NaHCO3, brine and dried over magnesium sulfate or sodium sulfate. Removal of the solvents at reduced pressure gave the title compound as a clear oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06849650B2 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-3f7d1b842cd34c0a9f136902c629ac0f |
| 출처 메모 | uspto-grants-2005_02 |