2-Thiopheneglyoxylic acid → 6-Nitro-3-thiophen-2-yl-1H-quinoxalin-2-one

반응식

[N+:1]([C:4]1[CH:5]=[C:6]([NH2:11])[C:7]([NH2:10])=[CH:8][CH:9]=1)([O-:3])=[O:2].[S:12]1[CH:16]=[CH:15][CH:14]=[C:13]1[C:17](=O)[C:18](O)=[O:19]>>[N+:1]([C:4]1[CH:5]=[C:6]2[C:7](=[CH:8][CH:9]=1)[NH:10][C:18](=[O:19])[C:17]([C:13]1[S:12][CH:16]=[CH:15][CH:14]=1)=[N:11]2)([O-:3])=[O:2]

참가 물질

반응물 2

HCID 776942-Thiopheneglyoxylic acid

HCID 51117914-Nitro-1,2-phenylenediamine

생성물 1

HCID 210836686-Nitro-3-thiophen-2-yl-1H-quinoxalin-2-one

실험 절차

The quinoxalin-2-one of the present example is prepared with 4-Nitro-benzene-1,2-diamine and (thiophen-2-yl) oxo-acetic acid via the method described in Example 12 to afford 6-Nitro-3-thiophen-2-yl-1H-quinoxalin-2-one.

출처 및 근거

ORD 기록: ord-60a9927419b74e44b9c218374c8dd0f5
출처 데이터셋: uspto-grants-2009_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07566719B2

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