Ethyl pyruvate → N-(3-trifluoromethyl4-chlorophenyl)alanine ethyl ester

반응식

[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][C:3]=1[C:9]([F:12])([F:11])[F:10].[C:13]([O:18][CH2:19][CH3:20])(=[O:17])[C:14]([CH3:16])=O>>[CH2:19]([O:18][C:13](=[O:17])[C@H:14]([CH3:16])[NH:6][C:5]1[CH:7]=[CH:8][C:2]([Cl:1])=[C:3]([C:9]([F:10])([F:11])[F:12])[CH:4]=1)[CH3:20]

참가 물질

반응물 2

HCID 12041Ethyl pyruvate

HCID 675744-Chloro-3-(trifluoromethyl)aniline

생성물 1

HCID 15434837N-(3-trifluoromethyl4-chlorophenyl)alanine ethyl ester

실험 절차

Following General Procedure AA above and using 4-chloro-3-(trifluoromethyl)aniline (Aldrich) and ethyl pyruvate (Aldrich), the title compound was prepared.

출처 및 근거

ORD 기록: ord-363a817140cc419793d2d9506acd69d8
출처 데이터셋: uspto-grants-2005_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06849650B2

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