Imidazole → 2-(Imidazol-1-yl)-5-methyl-4-(3-chloro-4-methoxybenzylamino)-thieno-(2,3-d]-pyrimidine

HRID 2302394노트

반응식

HRID 2302394 반응식
[NH:1]1[CH:5]=[CH:4][N:3]=[CH:2]1.Cl[C:7]1[N:8]=[C:9]([NH:17][CH2:18][C:19]2[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[C:21]([Cl:27])[CH:20]=2)[C:10]2[C:15]([CH3:16])=[CH:14][S:13][C:11]=2[N:12]=1>>[N:1]1([C:7]2[N:8]=[C:9]([NH:17][CH2:18][C:19]3[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[C:21]([Cl:27])[CH:20]=3)[C:10]3[C:15]([CH3:16])=[CH:14][S:13][C:11]=3[N:12]=2)[CH:5]=[CH:4][N:3]=[CH:2]1

참가 물질

3

반응물 2

HCID 795ImidazoleHCID 184604402-Chloro-5-methyl-4-(3-chloro-4-methoxybenzylamino)-thieno-[2,3-d]-pyrimidine

생성물 1

HCID 99300442-(Imidazol-1-yl)-5-methyl-4-(3-chloro-4-methoxybenzylamino)-thieno-(2,3-d]-pyrimidine

실험 절차

Following the procedure of Example 97, the reaction of imidazole with 2-chloro-5-methyl-4-(3-chloro-4-methoxybenzylamino)-thieno-[2,3-d]-pyrimidine gives 2-(imidazol-1-yl)-5-methyl-4-(3-chloro-4-methoxybenzylamino)-thieno-(2,3-d]-pyrimidine.

출처 및 근거

ORD 기록
ord-c6f6040707f3469b82b569a84e1feb34
출처 데이터셋
uspto-grants-2002_08
특허 번호
US06432950B1

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