Benzenemethanamine, 3,4-dichloro- → 2-(Pyridin-4-yl)-4-(3,4-dichlorobenzylamino)-6-chloro-thieno-[2,3-d]-pyrimidine

HRID 2302892노트

반응식

HRID 2302892 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[Cl:10])[CH2:5][NH2:6].Cl[C:12]1[C:13]2[CH:26]=[C:25]([Cl:27])[S:24][C:14]=2[N:15]=[C:16]([C:18]2[CH:23]=[CH:22][N:21]=[CH:20][CH:19]=2)[N:17]=1>>[N:21]1[CH:20]=[CH:19][C:18]([C:16]2[N:17]=[C:12]([NH:6][CH2:5][C:4]3[CH:7]=[CH:8][C:9]([Cl:10])=[C:2]([Cl:1])[CH:3]=3)[C:13]3[CH:26]=[C:25]([Cl:27])[S:24][C:14]=3[N:15]=2)=[CH:23][CH:22]=1

참가 물질

3

반응물 2

HCID 1608Benzenemethanamine, 3,4-dichloro-HCID 184599134-Chloro-2-(pyridin-4-yl)-6-chloro-thieno-[2,3-d]-pyrimidine

생성물 1

HCID 184601772-(Pyridin-4-yl)-4-(3,4-dichlorobenzylamino)-6-chloro-thieno-[2,3-d]-pyrimidine

실험 절차

With the procedure of Example 1, the reaction of 3,4-dichlorobenzylamine with 4-chloro-2-(pyridin-4-yl)-6-chloro-thieno-[2,3-d]-pyrimidine yields 2-(pyridin-4-yl)-4-(3,4-dichlorobenzylamino)-6-chloro-thieno-[2,3-d]-pyrimidine.

출처 및 근거

ORD 기록
ord-ee542fd158df40ee96b7ad221d24b85a
출처 데이터셋
uspto-grants-2002_08
특허 번호
US06432950B1

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