Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Chloro-4-fluorobenzonitrile → n-(3-Chloro-4-cyanophenyl)alanine iso-butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Chloro-4-fluorobenzonitrile | HCID 109000 | — |
| 반응물 | 2-Methylpropyl 2-aminopropanoate hydrochloride | HCID 86200109 | — |
| 생성물 | n-(3-Chloro-4-cyanophenyl)alanine iso-butyl ester | HCID 53791223 | — |
반응 단계
Following General Procedure AP above and using 2-chloro-4-fluorobenzonitrile (Aldrich) and D,L-alanine iso-butyl ester hydrochloride (from Example AA above), the title compound was prepared. The product was recovered by column chromatography on silica gel using 1:5 EtOAc/hexanes as the eluant.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06849650B2 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-a4bbed5dd2044f3fadb7ea98748fef7c |
| 출처 메모 | uspto-grants-2005_02 |