Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Barnidipine Hydrochloride → Barnidipine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Barnidipine Hydrochloride | HCID 443868 | — |
| 용매 | Methanol--water (1/1) | HCID 22242641 | — |
| 생성물 | Barnidipine | HCID 443869 | — |
반응 단계
Barnidipine hydrochloride, TC-5E and HCO-40 were dissolved in water-methanol (1:9). Separately, PEG20000 and POLYOX303 were mixed. Using a fluidized-bed granulator, the latter mixture was sprayed with the above solution. The granules thus prepared were dried, and after addition of lubricant, the composition was compression-molded to provide tablets each measuring 9.0 mm in diameter and 300 mg (barnidipine HCl content: 15 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06436441B1 |
| 출처 데이터셋 | uspto-grants-2002_08 |
| ORD ID | ord-5083954987584dcebe4b8bdc7143a1f3 |
| 출처 메모 | uspto-grants-2002_08 |