참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Bromine | HCID 24408 | — |
| 반응물 | 1-(4-Methoxyphenyl)-2-(pyridin-3-yl)ethanone | HCID 238351 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 2-Bromo-1-(4-methoxyphenyl)-2-(3-pyridyl)ethanone hydrobromide | HCID 11463336 | 89% |
반응 단계
1-(4-Methoxyphenyl)-2-(3-pyridyl)ethanone (6.85 g) was dissolved in acetic acid (36 mL), bromine (1.7 mL) was added to the solution and the resulting mixture was stirred at 80° C. for 3 h. After the mixture was cooled with ice-water, the crude crystalline mass was collected by filtration. The crude crystalline was recrystallized from ethanol-ethyl ether to afford the title compound (10.4 g, yield 89%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06436966B1 |
|---|
| 출처 데이터셋 | uspto-grants-2002_08 |
|---|
| ORD ID | ord-c9ddeea271f844e09d0c4b59aff5402c |
|---|
| 출처 메모 | uspto-grants-2002_08 |
|---|
