3-Amino-1,2-propanediol → (RS)-3-(2-Chroman-6-yl-quinolin-4-ylamino)-propane-1,2-diol hydrochloride

반응식

[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([C:12]2[CH:13]=[C:14]3[C:19](=[CH:20][CH:21]=2)[O:18][CH2:17][CH2:16][CH2:15]3)[CH:3]=1.[NH2:22][CH2:23][CH:24]([OH:27])[CH2:25][OH:26]>>[ClH:1].[O:18]1[C:19]2[C:14](=[CH:13][C:12]([C:4]3[CH:3]=[C:2]([NH:22][CH2:23][CH:24]([OH:27])[CH2:25][OH:26])[C:11]4[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=4)[N:5]=3)=[CH:21][CH:20]=2)[CH2:15][CH2:16][CH2:17]1

참가 물질

반응물 2

HCID 735613-Amino-1,2-propanediol

HCID 184329544-Chloro-2-chroman-6-yl-quinoline

생성물 1

HCID 18433110(RS)-3-(2-Chroman-6-yl-quinolin-4-ylamino)-propane-1,2-diol hydrochloride

실험 절차

The title compound, MS: m/e=351.3 (M+Ht), was prepared from 4-chloro-2-chroman-6-yl-quinoline and (RS)-3-amino-1,2-propandiol.

출처 및 근거

ORD 기록: ord-9ba1ce7a39704bfc86f3de7b77ad123b
출처 데이터셋: uspto-grants-2002_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06440995B1

반응 노트

불러오는 중…