1-amino-3-(piperidin-1-yl)propan-2-ol → HCID 18432998, 화합물

HRID 2305538노트

반응식

HRID 2305538 반응식
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[C:4]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=2)[CH:3]=1.[NH2:20][CH2:21][CH:22]([OH:30])[CH2:23][N:24]1[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1>>[ClH:1].[CH3:19][O:18][C:15]1[CH:16]=[CH:17][C:12]([C:4]2[CH:3]=[C:2]([NH:20][CH2:21][CH:22]([OH:30])[CH2:23][N:24]3[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29]3)[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[N:5]=2)=[CH:13][CH:14]=1

참가 물질

3

반응물 2

HCID 121749921-amino-3-(piperidin-1-yl)propan-2-olHCID 15481382HCID 15481382, 화합물

생성물 1

HCID 18432998HCID 18432998, 화합물

실험 절차

The title compound, m.p. 269-272° C., and MS: m/e=392.3 (M+H+), was prepared from 4-chloro-2-(4-methoxy-phenyl)-quinoline and (RS)-1-amino-3-piperidin-1-yl-propan-2-ol.

출처 및 근거

ORD 기록
ord-6b2c85d613e74e8ca11c45cffff500a5
출처 데이터셋
uspto-grants-2002_08
특허 번호
US06440995B1

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