Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Naphthylamine → N-(2-naphthyl)alanine Ethyl Ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Naphthylamine | HCID 7057 | — |
| 반응물 | Ethyl pyruvate | HCID 12041 | — |
| 생성물 | N-(2-naphthyl)alanine Ethyl Ester | HCID 11345542 | — |
반응 단계
Following reductive amination General Procedure AA above and using 2-aminonaphthalene (Aldrich) and ethyl pyruvate (Aldrich), the title compound was prepared as a solid having a melting point of 52-56° C. The reaction was monitored by silica gel tlc (Rf=0.50 in 25% EtOAc/hexanes). Purification was by flash chromatography with silica gel using 25% EtOAc/hexanes as the eluant.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06849650B2 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-5197e12bfb334a10b3329c8112e9cee0 |
| 출처 메모 | uspto-grants-2005_02 |