(3,4-Dichloro-benzyl)-bis-(2-chloro-ethyl)-amine → HCID 11005920, 화합물

HRID 2305926노트

반응식

HRID 2305926 반응식
[CH2:1]([O:3][C:4](=[O:20])[CH2:5][S:6]([C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:16][CH2:17][CH2:18][CH3:19])=[CH:11][CH:10]=1)(=[O:8])=[O:7])[CH3:2].[Cl:21][C:22]1[CH:23]=[C:24]([CH:33]=[CH:34][C:35]=1[Cl:36])[CH2:25][N:26]([CH2:30][CH2:31]Cl)[CH2:27][CH2:28]Cl>>[CH2:1]([O:3][C:4]([C:5]1([S:6]([C:9]2[CH:10]=[CH:11][C:12]([O:15][CH2:16][CH2:17][CH2:18][CH3:19])=[CH:13][CH:14]=2)(=[O:7])=[O:8])[CH2:28][CH2:27][N:26]([CH2:25][C:24]2[CH:33]=[CH:34][C:35]([Cl:36])=[C:22]([Cl:21])[CH:23]=2)[CH2:30][CH2:31]1)=[O:20])[CH3:2]

참가 물질

3

반응물 2

HCID 413964(3,4-Dichloro-benzyl)-bis-(2-chloro-ethyl)-amineHCID 11808743HCID 11808743, 화합물

생성물 1

HCID 11005920HCID 11005920, 화합물

실험 절차

4-(4-Butoxy-benzenesulfonyl)-1-(3,4-dichloro-benzyl)-piperidine-4-carboxylic acid ethyl ester was prepared according to the general method outlined in example 83. Starting from (4-butoxy-benzenesulfonyl)acetic acid ethyl ester (13.2g 44 mmol) (3,4dichloro-benzyl)-bis-(2-chloro-ethyl)-amine (14.3g, mmol). Yield 14.1g (60%), white solid, MP 86° C.; MS: 527.9 (M+H)+

출처 및 근거

ORD 기록
ord-51c4350edd5448c0b4b73fed2a8e935e
출처 데이터셋
uspto-grants-2002_08
특허 번호
US06441023B1

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