Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
L-Alanine → 2-Methylpropyl (2S)-2-aminopropanoate hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | L-Alanine | HCID 5950 | — |
| 반응물 | Isobutanol | HCID 6560 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 생성물 | 2-Methylpropyl (2S)-2-aminopropanoate hydrochloride | HCID 86584981 | — |
반응 단계
A mixture of 35.64 g (0.4 mol) of (D,L)-alanine (Aldrich) (or L-alanine (Aldrich)); 44 mL (0.6 mol) of thionyl chloride (Aldrich) and 200 mL of isobutanol was refluxed for 1.5 hours and the volatiles were removed completely on a rotavapor of 90° C. under reduced pressure to give (D,L)-alanine iso-butyl ester hydrochloride (or L-alanine iso-butyl ester hydrochloride), which was pure enough to be used for further transformations.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06849650B2 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-67ada832f8c24662847c20f8da7631de |
| 출처 메모 | uspto-grants-2005_02 |