Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3,4-Dichlorophenylacetic acid → N-[(3,4dichlorophenyl)acetyl]-L-alanine iso-butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3,4-Dichlorophenylacetic acid | HCID 79874 | — |
| 반응물 | 2-Methylpropyl (2S)-2-aminopropanoate hydrochloride | HCID 86584981 | — |
| 생성물 | N-[(3,4dichlorophenyl)acetyl]-L-alanine iso-butyl ester | HCID 15481766 | — |
반응 단계
Following General Procedure BB and using 3,4-dichlorophenylacetic acid (Aldrich) and L-alanine iso-butyl ester hydrochloride (from Example BB above), the title compound was prepared as a solid having a melting point of 81°-83° C. The reaction was monitored by tlc on silica gel and purification was by extraction with Et2O followed by washes with aqueous K2CO3 and aqueous HCl.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06849650B2 |
| 출처 데이터셋 | uspto-grants-2005_02 |
| ORD ID | ord-7d225e1005844bdd97d5e8ce53944117 |
| 출처 메모 | uspto-grants-2005_02 |