Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrazine hydrate (1:1) → 3-Phenyl-4,5-dihydro-1H-pyrazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 반응물 | 3-(Dimethylamino)-1-phenyl-1-propanone | HCID 77042 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 3-Phenyl-4,5-dihydro-1H-pyrazole | HCID 589745 | 89.8% |
반응 단계
Hydrazine monohydrate (6.2 g) was dissolved in ethanol (12 ml). Thereto was dropwise added a solution of 3-(N,N-dimethylamino)propiophenone (5.4 g) dissolved in ethanol (10 ml) in a nitrogen atmosphere at room temperature. The resulting mixture was refluxed for 3 hours with heating. The reaction mixture was poured into ice water. Extraction with chloroform was conducted, followed by drying and concentration, to obtain 4 g of a title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06831083B2 |
| 출처 데이터셋 | uspto-grants-2004_12 |
| ORD ID | ord-83a156f60c7b4a8db71824ec8e439b8f |
| 출처 메모 | uspto-grants-2004_12 |