2'-TrifluoroMethyl-Biphenyl-4-Carbaldehyde → HCID 69721135, 화합물

반응식

[F:1][C:2]([F:18])([F:17])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9]1[CH:14]=[CH:13][C:12]([CH:15]=O)=[CH:11][CH:10]=1.[C@@H:19]1([NH2:29])[C:28]2[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=2)[CH2:22][CH2:21][CH2:20]1>>[C@@H:19]1([NH:29][CH2:15][C:12]2[CH:13]=[CH:14][C:9]([C:4]3[CH:5]=[CH:6][CH:7]=[CH:8][C:3]=3[C:2]([F:18])([F:17])[F:1])=[CH:10][CH:11]=2)[C:28]2[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=2)[CH2:22][CH2:21][CH2:20]1

참가 물질

반응물 2

HCID 13926532'-TrifluoroMethyl-Biphenyl-4-Carbaldehyde

HCID 70580741-Aminotetralin, (S)-

생성물 1

HCID 69721135HCID 69721135, 화합물

실험 절차

2′-(Trifluoromethyl)[1,1′-biphenyl]-4-carbaldehyde and (1S)-1,2,3,4-tetrahydro-1-naphthalenylamine were processed as described in Example 1A to provide the title compound.

출처 및 근거

ORD 기록: ord-6a1135053e5c46abbfc30f126e5424c7
출처 데이터셋: uspto-grants-2004_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06831193B2

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