4'-Trifluoromethyl-biphenyl-3-carbaldehyde → N-[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]-N-{[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methyl}amine
반응식
[F:1][C:2]([F:18])([F:17])[C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([CH:15]=O)[CH:10]=2)=[CH:5][CH:4]=1.[C@@H:19]1([NH2:29])[C:28]2[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=2)[CH2:22][CH2:21][CH2:20]1>>[C@@H:19]1([NH:29][CH2:15][C:11]2[CH:10]=[C:9]([C:6]3[CH:7]=[CH:8][C:3]([C:2]([F:18])([F:17])[F:1])=[CH:4][CH:5]=3)[CH:14]=[CH:13][CH:12]=2)[C:28]2[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=2)[CH2:22][CH2:21][CH2:20]1참가 물질
3
실험 절차
4′-(Trifluoromethyl)[1,1′-biphenyl]-3-carbaldehyde and (1S)-1,2,3,4-tetrahydro-1-naphthalenylamine were processed as described in Example 1A to provide the title compound.
출처 및 근거
- ORD 기록
- ord-7060e26b6a1f4ae7bf331c0a2a69e906
- 출처 데이터셋
- uspto-grants-2004_12
- 특허 번호
- US06831193B2
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