Hydroxylamine, O-(1-methylethyl)- → 5-({{3-[(isopropoxyimino)methyl]benzyl}[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]amino}carbonyl)-1,2,4-benzenetricarboxylic Acid

HRID 2307695노트

반응식

HRID 2307695 반응식
[CH:1]([C:3]1[CH:4]=[C:5]([CH:35]=[CH:36][CH:37]=1)[CH2:6][N:7]([C@@H:25]1[C:34]2[C:29](=[CH:30][CH:31]=[CH:32][CH:33]=2)[CH2:28][CH2:27][CH2:26]1)[C:8]([C:10]1[CH:15]=[C:14]([C:16]([OH:18])=[O:17])[C:13]([C:19]([OH:21])=[O:20])=[CH:12][C:11]=1[C:22]([OH:24])=[O:23])=[O:9])=O.[CH:38]([O:41][NH2:42])([CH3:40])[CH3:39]>>[CH:38]([O:41][N:42]=[CH:1][C:3]1[CH:4]=[C:5]([CH:35]=[CH:36][CH:37]=1)[CH2:6][N:7]([C@@H:25]1[C:34]2[C:29](=[CH:30][CH:31]=[CH:32][CH:33]=2)[CH2:28][CH2:27][CH2:26]1)[C:8]([C:10]1[CH:15]=[C:14]([C:16]([OH:18])=[O:17])[C:13]([C:19]([OH:21])=[O:20])=[CH:12][C:11]=1[C:22]([OH:24])=[O:23])=[O:9])([CH3:40])[CH3:39]

참가 물질

3

반응물 2

HCID 2768923Hydroxylamine, O-(1-methylethyl)-HCID 102288355-({(3-formylbenzyl)[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]amino}carbonyl)-1,2,4-benzenetricarboxylic Acid

생성물 1

HCID 865878465-({{3-[(isopropoxyimino)methyl]benzyl}[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]amino}carbonyl)-1,2,4-benzenetricarboxylic Acid

실험 절차

The product from Example 76E and O-isopropylhydroxylamine were processed as described in Example 76F to provide the title compound.

출처 및 근거

ORD 기록
ord-a88b256ba3ff4ab092d1635ed264717b
출처 데이터셋
uspto-grants-2004_12
특허 번호
US06831193B2

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