3,5-Dichlorophenylboronic acid → HCID 10189253, 화합물

HRID 2307702노트

반응식

HRID 2307702 반응식
Br[C:2]1[CH:3]=[C:4]([CH:34]=[CH:35][CH:36]=1)[CH2:5][N:6]([C@@H:24]1[C:33]2[C:28](=[CH:29][CH:30]=[CH:31][CH:32]=2)[CH2:27][CH2:26][CH2:25]1)[C:7]([C:9]1[CH:14]=[C:13]([C:15]([OH:17])=[O:16])[C:12]([C:18]([OH:20])=[O:19])=[CH:11][C:10]=1[C:21]([OH:23])=[O:22])=[O:8].[Cl:37][C:38]1[CH:39]=[C:40](B(O)O)[CH:41]=[C:42]([Cl:44])[CH:43]=1>>[Cl:37][C:38]1[CH:39]=[C:40]([C:2]2[CH:36]=[CH:35][CH:34]=[C:4]([CH2:5][N:6]([C@@H:24]3[C:33]4[C:28](=[CH:29][CH:30]=[CH:31][CH:32]=4)[CH2:27][CH2:26][CH2:25]3)[C:7]([C:9]3[CH:14]=[C:13]([C:15]([OH:17])=[O:16])[C:12]([C:18]([OH:20])=[O:19])=[CH:11][C:10]=3[C:21]([OH:23])=[O:22])=[O:8])[CH:3]=2)[CH:41]=[C:42]([Cl:44])[CH:43]=1

참가 물질

3

반응물 2

HCID 27343313,5-Dichlorophenylboronic acidHCID 10144017HCID 10144017, 화합물

생성물 1

HCID 10189253HCID 10189253, 화합물

실험 절차

The product from Example 15B (165 mg, 0.3 mmol) and 3,5-dichlorophenylboronic acid were processed as described in Example 85 to provide the title compound.

출처 및 근거

ORD 기록
ord-6a3d147acdc14c7698c5d58cc62dc9a8
출처 데이터셋
uspto-grants-2004_12
특허 번호
US06831193B2

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