6-Iodo-4-{[3-(methyloxy)phenyl]amino}-3-quinolinecarboxamide hydrochloride → 7-Chloro-6-iodo-4-{[3-(methyloxy)phenyl]amino}-3-quinolinecarboxamide hydrochloride
반응식
[ClH:1].[I:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[N:9]=[CH:8][C:7]([C:13]([NH2:15])=[O:14])=[C:6]2[NH:16][C:17]1[CH:22]=[CH:21][CH:20]=[C:19]([O:23][CH3:24])[CH:18]=1>C(#N)C>[ClH:1].[Cl:1][C:12]1[CH:11]=[C:10]2[C:5]([C:6]([NH:16][C:17]3[CH:22]=[CH:21][CH:20]=[C:19]([O:23][CH3:24])[CH:18]=3)=[C:7]([C:13]([NH2:15])=[O:14])[CH:8]=[N:9]2)=[CH:4][C:3]=1[I:2]참가 물질
3
실험 절차
Intermediate 63 was prepared from Intermediate 67 in a similar manner to Intermediate 14, using acetonitrile as solvent.
출처 및 근거
- ORD 기록
- ord-f91c6600c3114bf7beab1028533c3fad
- 출처 데이터셋
- uspto-grants-2009_07
- 특허 번호
- US07566786B2
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