4,6-Difluoro-1,3-benzothiazol-2-amine → 5-Methyl-thiophene-2-carboxylic acid (4,6-difluoro-benzothiazol-2-yl)-amide

HRID 2308429노트

반응식

HRID 2308429 반응식
[NH2:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([F:11])[CH:8]=[C:7]([F:12])[C:5]=2[N:6]=1.[CH3:13][C:14]1[S:18][C:17]([C:19](Cl)=[O:20])=[CH:16][CH:15]=1>>[F:12][C:7]1[C:5]2[N:6]=[C:2]([NH:1][C:19]([C:17]3[S:18][C:14]([CH3:13])=[CH:15][CH:16]=3)=[O:20])[S:3][C:4]=2[CH:10]=[C:9]([F:11])[CH:8]=1

참가 물질

3

반응물 2

HCID 7374064,6-Difluoro-1,3-benzothiazol-2-amineHCID 27600835-Methylthiophene-2-carbonyl chloride

생성물 1

HCID 865848975-Methyl-thiophene-2-carboxylic acid (4,6-difluoro-benzothiazol-2-yl)-amide

실험 절차

Using 2-amino-4,6-difluoro-benzothiazole and 5-methyl-thiophene-carboxylicacid chloride the title compound was prepared as a yellow solid (74% yield), MS: m/e=310 (M+).

출처 및 근거

ORD 기록
ord-3076a00d4a0344dab51fa341fc2716fa
출처 데이터셋
uspto-grants-2004_12
특허 번호
US06835732B2

반응 노트

불러오는 중…