Sodium Methoxide → (5-Methoxy-biphenyl-3-yl)-thiourea
반응식
C([NH:9][C:10]([NH:12][C:13]1[CH:14]=[C:15]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[CH:16]=[C:17]([O:19][CH3:20])[CH:18]=1)=[S:11])(=O)C1C=CC=CC=1.C[O-].[Na+]>CO>[CH3:20][O:19][C:17]1[CH:18]=[C:13]([NH:12][C:10]([NH2:9])=[S:11])[CH:14]=[C:15]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[CH:16]=1참가 물질
4
실험 절차
1-Benzoyl-3-(5-methoxy-biphenyl-3-yl)-thiourea (183 mg, 0.51 mmol) in methanol (5 ml) are treated with sodium methoxide (5.4M in methanol, 0.14 ml) and the formed precipitate is filtered off. Washing with methanol yields the product (115 mg, 88%) as off-white powder. MS: m/e=258 (M+).
후처리
- filtrationthe formed precipitate is filtered off
- washWashing with methanol
출처 및 근거
- ORD 기록
- ord-1da8584fab624b88867a2bcf25ae0559
- 출처 데이터셋
- uspto-grants-2004_12
- 특허 번호
- US06835732B2
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