Piperazine → 8-Methylthio-2-piperazino-4-thiomorpholino-pyrimido-[5,4-d]-pyrimidine

HRID 2308622

반응식

HRID 2308622 반응식
Cl[C:2]1[N:3]=[C:4]([N:14]2[CH2:19][CH2:18][S:17][CH2:16][CH2:15]2)[C:5]2[N:11]=[CH:10][N:9]=[C:8]([S:12][CH3:13])[C:6]=2[N:7]=1.[NH:20]1[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]1>>[CH3:13][S:12][C:8]1[C:6]2[N:7]=[C:2]([N:20]3[CH2:25][CH2:24][NH:23][CH2:22][CH2:21]3)[N:3]=[C:4]([N:14]3[CH2:19][CH2:18][S:17][CH2:16][CH2:15]3)[C:5]=2[N:11]=[CH:10][N:9]=1

참가 물질

3

반응물 2

HCID 4837PiperazineHCID 201501712-Chloro-8-methylthio-4-thiomorpholino-pyrimido-[5,4-d]-pyrimidine

생성물 1

HCID 201502198-Methylthio-2-piperazino-4-thiomorpholino-pyrimido-[5,4-d]-pyrimidine

실험 절차

This compound was prepared analogous to Example 2 from 2-chloro-8-methylthio-4-thiomorpholino-pyrimido-[5,4-d]-pyrimidine (m.p.: 165°-167° C.) and piperazine at room temperature.

출처 및 근거

ORD 기록
ord-fddc9394d2fe4309b3debfbf51b2ab57
출처 데이터셋
uspto-grants-1987_09
특허 번호
US04690923

연결된 노트

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