Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
L-Tryptophan → 2-[(4-chlorophenyl)formamido]-3-(1H-indol-3-yl)propanoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | L-Tryptophan | HCID 6305 | — |
| 반응물 | 4-Chlorobenzoyl chloride | HCID 8501 | — |
| 생성물 | 2-[(4-chlorophenyl)formamido]-3-(1H-indol-3-yl)propanoic acid | HCID 2787526 | 79.2% |
반응 단계
By using 10 g of L-tryptophane and 9 g of 4-chlorobenzoyl chloride, and a method similar to that described in reference example 6, recrystallized from methanol-water there was obtained 13.3 g of 2-(4-chlorobenzoylamino)-3-(indol-3-yl)propionic acid in the form of colorless needle-like crystals. Melting point: 100°-102° C. [α]D25 -49.3° (C=1, methanol)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04694017 |
| 출처 데이터셋 | uspto-grants-1987_09 |
| ORD ID | ord-6cb5cc7566c5475a81c2b4ea40e7bc08 |
| 출처 메모 | uspto-grants-1987_09 |