Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 2309860생성일: 2026년 10월 27일
2,3-Diaminopyridine → 2-(2'-Methoxy-4'-chlorosulfonyl-phenyl)-imidazo[4,5-b]pyridine hydrochloride
https://huagongshe.com/reaction/2309860
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 2,3-Diaminopyridine | HCID 9956 | — |
| 반응물 | 4-Amino-o-anisic acid | HCID 75599 | — |
| 반응물 | 4-(Chlorosulfonyl)-2-methoxybenzoic acid | HCID 20184580 | — |
| 용매 | Phosphorus oxychloride | HCID 24813 | — |
| 생성물 | 2-(2'-Methoxy-4'-chlorosulfonyl-phenyl)-imidazo[4,5-b]pyridine hydrochloride | HCID 20184517 | — |
반응 단계
Five grams of 2-methoxy-4-chlorosulfonyl-benzoic acid (prepared from 4-amino-2-methoxy-benzoic acid via the corresponding diazonium compound) were dissolved in 400 ml of phosphorus oxychloride and heated to 80° C. for 30 minutes. Then, 3.6 mg of 2,3-diaminopyridine were added, and the mixture was refluxed for four hours. The reaction mixture was concentrated by evaporation in vacuo and re-evaporated with toluene, and the solid residue was processed further without any other purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04696931 |
|---|
| 출처 데이터셋 | uspto-grants-1987_09 |
|---|
| ORD ID | ord-5f3989f4c3714807afddf293f35354b6 |
|---|
| 출처 메모 | uspto-grants-1987_09 |
|---|
