4,5-Diaminopyrimidine → N-[2-Methoxy-4-(7H-purin-8-yl)phenyl]methanesulfonamide

반응식

[NH2:1][C:2]1[C:7]([NH2:8])=[CH:6][N:5]=[CH:4][N:3]=1.[CH3:9][O:10][C:11]1[CH:12]=[C:13]([CH:17]=[CH:18][C:19]=1[NH:20][S:21]([CH3:24])(=[O:23])=[O:22])[C:14](O)=O>>[CH3:9][O:10][C:11]1[CH:12]=[C:13]([C:14]2[NH:8][C:7]3[C:2](=[N:3][CH:4]=[N:5][CH:6]=3)[N:1]=2)[CH:17]=[CH:18][C:19]=1[NH:20][S:21]([CH3:24])(=[O:23])=[O:22]

참가 물질

반응물 2

HCID 837034,5-Diaminopyrimidine

HCID 201845274-[(Methanesulfonyl)amino]-3-methoxybenzoic acid

생성물 1

HCID 13284524N-[2-Methoxy-4-(7H-purin-8-yl)phenyl]methanesulfonamide

실험 절차

Prepared analogously to Example 14 from 4,5-diaminopyrimidine and 3-methoxy-4-methanesulfonylamino-benzoic acid.

출처 및 근거

ORD 기록: ord-a2d52b2714f14f968e6c98cd6f757972
출처 데이터셋: uspto-grants-1987_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04696931

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