Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Hydroxybenzoic Acid → Benzoic acid, 4-hydroxy-, 2-methylbutyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Hydroxybenzoic Acid | HCID 135 | — |
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | (S)-2-methyl-1-butanol | HCID 2723602 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | Benzoic acid, 4-hydroxy-, 2-methylbutyl ester | HCID 13530949 | 88.1% |
반응 단계
0.29 mole(40.0 g) of 4-hydroxybenzoic acid and 0.35 mole(30.9 g) of (S)-(-)-2-methylbutanol were refluxed for 20 hours in 150 ml of toluene in the presence of 1 ml of conc. sulfuric acid. The reaction solution was concentrated, and then purified by column chromatography to obtain 53.2 g of 4-hydroxybenzoic acid 2-methylbutyl ester [[α]D23 =+4.95°(CHCl3)]. (yield: 88%)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04844835 |
| 출처 데이터셋 | uspto-grants-1989_07 |
| ORD ID | ord-469b52153c964ebba05ae7f9953356b8 |
| 출처 메모 | uspto-grants-1989_07 |