Dichloromethane → 3-cyclopentyl-2-(3-fluoro-4-hydroxy-phenyl)-N-thiazol-2-yl-propionamide

반응식

[B:25]([Br:26])([Br:27])[Br:28].[CH2:29]([Cl:30])[Cl:31].[CH:1]1([CH2:6][CH:7]([C:8](=[O:9])[NH:10][c:11]2[s:12][cH:13][cH:14][n:15]2)[c:16]2[cH:17][c:18]([F:24])[c:19]([O:22][CH3:23])[cH:20][cH:21]2)[CH2:2][CH2:3][CH2:4][CH2:5]1>>[CH:1]1([CH2:6][CH:7]([C:8](=[O:9])[NH:10][c:11]2[s:12][cH:13][cH:14][n:15]2)[c:16]2[cH:17][c:18]([F:24])[c:19]([OH:22])[cH:20][cH:21]2)[CH2:2][CH2:3][CH2:4][CH2:5]1

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 25134Boron tribromide

HCID 223151793-cyclopentyl-2-(3-fluoro-4-methoxy-phenyl)-N-thiazol-2-yl-propionamide

생성물 1

HCID 223152383-cyclopentyl-2-(3-fluoro-4-hydroxy-phenyl)-N-thiazol-2-yl-propionamide

출처 및 근거

ORD 기록: ord-8b8cc586ae6f40748c5b17a512d49a18
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

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