참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 4,4'-Dichlorobenzhydryl chloride | HCID 13078 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | HCID 178418936 | HCID 178418936 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 1-[bis(4-chlorophenyl)methyl]-1H-1,2,3-triazole | HCID 14390654 | — |
| 생성물 | 2-[bis(4-chlorophenyl)methyl]-2H-1,2,3-triazole | HCID 20034902 | — |
반응 단계
Following the general procedure of Example 1B, 5.0 g of 1,2,3-triazole in 100 ml fo dimethylformamide were treated first with 1.44 g of sodium hydride (60% in mineral oil), and then with 5.0 g of 4.4'-dichlorobenzhydryl chloride. The reactants were stirred overnight at about 25° C. and then heated for 1 hour on a steam bath. Chromatography of the residue after work-up provided 2.4 g of the undesired 2-[bis(4-chlorophenyl)methyl]-2H-1,2,3-triazole and 3.1 g of the desired title product, m.p. 124°-125° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04845227 |
|---|
| 출처 데이터셋 | uspto-grants-1989_07 |
|---|
| ORD ID | ord-809019cea303426b8bafa091cd2074d2 |
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| 출처 메모 | uspto-grants-1989_07 |
|---|
