alpha-Hydroxy-gamma-butyrolactone → N-[1-[4-[3-chloro-4-(1,3-thiazol-4-ylmethoxy)anilino]quinazolin-5-yl]oxypropan-2-yl]-2,4-dihydroxybutanamide

반응식

[NH2:1][CH:2]([CH2:3][O:4][c:5]1[c:6]2[c:7]([NH:15][c:16]3[cH:17][c:18]([Cl:29])[c:19]([O:22][CH2:23][c:24]4[n:25][cH:26][s:27][cH:28]4)[cH:20][cH:21]3)[n:8][cH:9][n:10][c:11]2[cH:12][cH:13][cH:14]1)[CH3:30].[OH:31][CH:32]1[C:33](=[O:34])[O:35][CH2:36][CH2:37]1>>[NH:1]([CH:2]([CH2:3][O:4][c:5]1[c:6]2[c:7]([NH:15][c:16]3[cH:17][c:18]([Cl:29])[c:19]([O:22][CH2:23][c:24]4[n:25][cH:26][s:27][cH:28]4)[cH:20][cH:21]3)[n:8][cH:9][n:10][c:11]2[cH:12][cH:13][cH:14]1)[CH3:30])[C:33]([CH:32]([OH:31])[CH2:37][CH2:36][OH:35])=[O:34]

참가 물질

반응물 2

HCID 545831alpha-Hydroxy-gamma-butyrolactone

HCID 178464743HCID 178464743, 화합물

생성물 1

HCID 11284176N-[1-[4-[3-chloro-4-(1,3-thiazol-4-ylmethoxy)anilino]quinazolin-5-yl]oxypropan-2-yl]-2,4-dihydroxybutanamide

출처 및 근거

ORD 기록: ord-9b2647cef8194f548ed6e7534da2ce03
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

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