Methanol → Methyl L-ornithine monohydrochloride

HRID 23131

반응식

HRID 23131 반응식
[ClH:1].[NH2:2][C@H:3]([C:8]([OH:10])=[O:9])[CH2:4][CH2:5][CH2:6][NH2:7].[CH3:11]O>>[ClH:1].[CH3:11][O:9][C:8](=[O:10])[C@H:3]([CH2:4][CH2:5][CH2:6][NH2:7])[NH2:2]

참가 물질

3

반응물 2

HCID 887MethanolHCID 76654Ornithine hydrochloride

생성물 1

HCID 6453904Methyl L-ornithine monohydrochloride수율 97%

실험 절차

Into a stirred suspension of L-(+)-ornithine hydrochloride (Aldrich) in methanol was bubbled anhydrous hydrochloric acid gas until the solution was saturated. The reaction mixture was capped with a rubber septum and stirring was continued overnight at room temperature. The solvent was then stripped under reduced pressure and the residue triturated with ether. The resulting solid was dried under reduced pressure to afford L-(+)-ornithine methyl ester hydrochloride as a white solid (97% yield).

후처리

  1. customwas bubbled anhydrous hydrochloric acid gas until the solution
  2. customThe reaction mixture was capped with a rubber septum
  3. customthe residue triturated with ether
  4. customThe resulting solid was dried under reduced pressure

출처 및 근거

ORD 기록
ord-2ce35a539b1e4ded93924c2d28580b37
출처 데이터셋
uspto-grants-2005_02
특허 번호
US06849650B2

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